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00:05 What is wrong in metabolic syndrome
00:46 Wastes pile up in metabolic syndrome
01:17 A heart attack waiting to happen
02:13 The waste disposal department
02:42 Scheduling waste removal
03:17 Meet the dustbin men
04:02 The cell’s garbage disposal unit
04:25 Recycling amino acids etc
05:02 In the insulin resistant….
05:47 What’s going on in insulin resistance ?
06:03 Dustbin men activity
06:32 Less autophagy
06:58 Cells don’t multi-task
07:23 In the presence of insulin….
07:42 Cleaning up barely happens
08:03 Wastes pile up
Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia.
THE JOURNAL OF BIOLOGICAL CHEMISTRY (2009) 284(45):31484–31492.
Hui-Yu Liu, Jianmin Han, Sophia Y. Cao, Tao Hong, Degen Zhuo, Jianbo Shi,
Zhenqi Liu and Wenhong Cao.